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What is the most important blood pressure-lowering drugs?

Diuretic medications (diuretics) increase the secretion of water and salt through the kidneys, so that urine production is greater. This reduces the amount of fluid in blood vessels and blood pressure drops. The drugs also have a certain effect on the blood vessels so that they expand somewhat. Thus, lowered blood pressure even further.

Diuretic medications are among the most important drugs in the treatment of high blood pressure (hypertension). These funds are especially useful in people who also have heart failure.

Special diuretic drugs (thiazides) should be used with caution in diabetes. They may complicate control of blood sugar. Conditions that cause disturbances in the body's salt balance, can be problematic when using diuretic medications.

Diuretic medications often produce frequent urination. Serious side effects are rare with the use of diuretic medications. Some may have nausea, constipation or diarrhea, and some are bothered by fatigue and impotence.

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To reduce the risk of side effects it is important to use the medicine properly. This requires regular medical checkups, including blood tests. Especially in the beginning of treatment is necessary.

ACE inhibitors
ACE inhibitors are a group of drugs that make the blood vessels to relax and dilate, reducing blood pressure and improve blood flow in small vessels in addition to the blood pressure-lowering effect, ACE inhibitors, a weak diuretic (diuretic) effect. This enhances blood pressure reduction.

ACE inhibitors are used widely in people with high blood pressure (hypertension), especially in those who in addition to high blood pressure have heart failure or diabetes.

People with narrowing of the renal arteries or heart valves should be carefully monitored when initiating treatment with ACE inhibitors and angiotensin receptor related block holders. The expected pregnancy, during pregnancy and lactation, these agents do not use.

During normal use, giving ACE inhibitors usually few or no side effects. Some people, particularly women, get 1/1 cough, especially at night. Other side effects are reduced sense of taste, fatigue, nausea, dizziness, fainting tendency, headache and itching.

Beta-blockers
Beta-blockers reduce the heart's workload by slowing the heart rate (pulse) and the amount of blood pumped out with each stroke. Beta-blockers also slows metabolism of the heart muscle. All these effects lead to reduced blood pressure and less need for oxygen to the heart muscle. The downside is that your physical performance may be somewhat poorer.

Beta-blockers have until recently been one of the medications tried first in people with high blood pressure. It Must have a good effect, and they are relatively inexpensive. This type of drug is also used by most who have had heart attacks, and then it reduces the risk of new attacks. In addition, it is often effective at angina pectoris ("angina"). In recent years, beta-blockers had a more uncertain place in the treatment of high blood pressure, and they used less than before. In the UK, guidelines have been removed, for example, beta-blockers as first choice.

People with definite illnesses should be careful to use beta-blockers. These include diabetes, asthma and COPD, heart failure and certain cardiac arrhythmias. The effect of beta-blockers decreases with age.

The side effects vary from person to person and is also dose dependent. The most common problems are muscle fatigue during exercise, cold hands and feet, and fatigue.

It is very important that you do not stop abruptly with beta-blockers. Downsizing will occur gradually over several weeks and only in consultation with your doctor. Too rapid reduction can sometimes have serious consequences, such as rising blood pressure, heart attack or brain hemorrhage.

Calcium blockers
Calcium channel blockers (calcium antagonists) seem a number of places in the cardiovascular system. They make the blood vessels to dilate, lowering the heart rate and damping force of the heartbeat. This reduces strain on the heart and improves blood flow through narrow blood vessels.

The medicine can be used to treat high blood pressure. It is usually not alone, but as well as other blood pressure medications such as beta blockers or ACE inhibitors.

Common side effects of calcium-channel blockers are dizziness and fainting tendency, headache, nausea, flushing, vannstuvning around the legs, heart palpitations and possible slow heartbeat.

Angiotensin 2-block
Angiotensin 2-block similar to ACE inhibitors. The effect on high blood pressure is pleasant, especially shows angiotensin 2-block holders a pleasurable effect on reducing stroke. Side effects are more rare than the use of ACE inhibitors, but to return the price higher.





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